Feed-grade Zinc Oxide ZnO Used to Control Diarrhea in Piglets
European Commission President Ursula von der Leyen recently called on India and other countries to support sanctions against Russia over the Ukraine incident. At The Raisina Dialogue forum, von der Leyen said, "We earnestly appeal to all members of the international community to support our efforts to achieve lasting peace."
Von der Leyen says countries around the world that have been suffering from the virus for two years must now deal with higher food, energy, and fertilizer prices. What is happening in Ukraine will not only determine the future of Europe, but also have profound implications for the rest of the world.
Because of the Russia-Ukraine conflict, the prices of many other commodities like the zinc oxide are expected to continue to rise in the future.
Zinc oxide is an oxide of zinc. Insoluble in water, soluble in acids and strong bases. Zinc oxide is mainly used in chemical industry, pharmaceutical industry, agriculture and other fields.
Feed-grade zinc oxide has a significant effect on the safe control of piglet diarrhea. However, zinc oxide will also cause rough coat of piglets, unbalanced absorption of trace elements, late growth retardation, environmental pollution and other problems. Therefore, feed-grade zinc oxide is a double-edged sword in controlling diarrhea in piglets.
Zinc oxide does have a good effect on controlling diarrhea. But zinc oxide as an amphoteric oxide, first of all, more than 70% of zinc oxide in gastric acid can not pass safely in the form of functional molecular state ZnO, and is transformed into Zn2+ which has no diarrhea control effect. Not to mention the destruction of bile and small intestinal fluid in the intestine. This is an important reason why a large amount of zinc oxide must be added to ensure that enough ZnO reaches the intestinal tract to play a role and achieve a good diarrhea control effect. For those dissolved Zn2+, will be over-absorbed, high blood zinc concentration, resulting in adverse effects on piglet coat color, growth speed and immune function.
So how to maximize the efficacy of zinc oxide, let the zinc of 1500ppm (based on zinc) play the role and effect of 3000ppm under conventional conditions, so that zinc oxide is not destroyed by digestive juices such as gastric acid, and exists and evenly dispersed in the intestinal tract in the form of molecular ZnO in its effective form?
How to deal with it?
Acid resistance, compatibility with chyme and lipophilicity are the decisive factors that determine whether zinc oxide can maximize the effect of antidiarrheal convergence. Only when zinc oxide is acid-resistant, can it not be neutralized by gastric acid, and can it reach the intestinal tract with molecular zinc oxide particles that can control diarrhea; only when zinc oxide is compatible with chyme can it be rapidly and uniformly dispersed in the intestinal tract and form a uniform protective film on the surface of the entire intestinal mucosa; only when zinc oxide is lipophilic, it can be in close contact with the intestinal mucosa of lipids and enrich to the surface of the intestinal mucosa, and the effect will be better.
How to treat zinc oxide with acid resistance? How to make zinc oxide disperse evenly in the intestines? How to make zinc oxide in close contact with intestinal mucosa? It is a problem that the manufacturer needs to solve.
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Luoyang Tongrun Nano Technology is a trusted chemical supplier and manufacturer providing high-quality chemicals and Nanomaterials. If you are looking for the zinc oxide, please feel free to contact us and send an inquiry.